When Bender accidentally causes the Professor's 'What If' machine to explode, the city of New New York is divided into multiple 'What If' scenarios. Only Bender and Fry are unaffected and must gather the parts needed to repair the machine to return things to normal. They enlist the help of a Zoidberg who is from a world where he is incredibly lucky, a Leela who never left the mutant underground and is painfully shy, and a Professor who just happens to be a kangaroo.