In Pandemic: Iberia, the year is 1848, and diseases are spreading fast under the burning sun of the Iberian Peninsula. Take on the roles of a nurse, a railway man, and a rural doctor, among many others, and work as a team to push back the new threats that are malaria, typhus, cholera, and the yellow fever. From Barcelona to Lisboa, travel by carriage, by boat, or by train, and help the Iberian populace by developing railways and distributing purified water.