Designed by David Turczi, Defense of Procyon III is a highly asymmetric game of four players in two teams: one player takes charge of the Alien space navy, one the Alien ground force, while the other team of the Human space navy admiral and the ground forces' commander stands in their way. The space board uses a hex board, while the ground board is a point-to-point network of locations. The game is played over 12 turns, using card-driven, low luck mechanisms that quickly unfold into a fast-paced game of combat strategy - presented with countless high-quality miniatures in a rich, thematic world.

The two commanders of a side will have to work together closely to make sure there are no weaknesses for the enemy to exploit, yet their different mechanisms and different theaters will ensure each player is comfortably occupied with their own responsibilities - avoiding the alpha player issue common in team games. The game also comes with an automated opponent that takes charge of one of the sides. One or two players can play cooperatively against the opponent.