Pamela Isley has been a lot of things in her life. A living god, a super-villain, an activist, a scientist, and dead. In a new body that she didn't ask for and with a renewed sense of purpose, Ivy leaves Gotham and sets out to complete her greatest work-a gift to the world that will heal the damage dealt to it...by ending humanity. On her journey to doom humankind, a heartbroken and betrayed Poison Ivy encounters obstacles (plant assassins!) and dodges the law along the way, in a body horror-infused character-defining epic from the visionary creative team of writer G. Willow Wilson and artist Marcio Takara. This volume collects Poison Ivy #1-6.